Proteins are the functional units responsible for carrying out all biological processes and control cellular function. The life cycle of proteins is determined
by 3 phases:
Integrating cutting edge solutions with unmet clinical needs:
our unique and proprietary technologies
PTM Biosciences is employing innovative and state-of-the art epiProteomic solutions conceived by Yifat Merbl, PhD, that provide the most relevant information to disease phenotype and pathological state, generating proprietary, novel data for biomarker discovery & therapeutics.
Our edge is tackling different aspects from most of the current personalized medicine approaches, namely the protein modifications (PTM Profiling).
Integrating this unique approach and datasets of the protein modifications, with specific algorithmic and computational tools, provides an unparalleled view on this layer of regulation that is currently not accessible.
After a protein is being made it undergoes multiple chemical changes and modifications which are called post-translational modifications (PTM). PTMs determine proteins' function, stability, cellular localization and even their binding partners
The PTM profiling technology allows high throughput analysis of protein modifications. We analyze liquid biopsies and tissue biopsies of diverse clinical conditions and utilizing Artificial Intelligence, we gain insight into the tissue function and activity, integrating protein modifications into novel targets for biomarker discovery and therapeutics.
PRODUCT LINE - PROGNOSTIC KITS
for predicting benefit of drugs
for predicting disease progression
PRODUCT LINE - THERAPEUTIC TARGETS
Novel therapeutic targets for T cell-mediated therapies (e.g. anti-cancer vaccines)
Our technologies are based on scientific publication in leading journals